ActSep®CD3/CD28 Separation & Activation Magnetic Beads

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T&L Biotechnology

Business Type:Others

Country/Region:China

Ddu Verified

HOT Rank

8/10

Product Information

  • Pharmacopeia:IP
  • Shelf Life:2 years
  • Storage:Sealed
  • Place of Origin:China

Description

Catalog Number: GMP-TL603


Product Name


Generic Name


ActSep®CD3/CD28 Separation & Activation Magnetic Beads


Product Information

Consistence

2×108 beads / mL

Content

1mL

Endotoxin

< 0.5 EU/mL

Reactive species

human

Storage Temperature

2~8℃

Validity period

24 months


Product Description


ActSep®CD3/CD28 Separation & Activation Magnetic Beads are suitable for separation of human CD3+T cells, providing a simple method for activating and expanding human T cells without the need for antigen presenting cells and antigens. By coupling anti-human CD3 and anti-human CD28 antibodies on magnetic beads, the primary and co-stimulatory signals needed to regulate T cell activation and expansion are provided. The beads are suitable for human T cell separation, activation and expansion, CAR-T and other T cell culture applications.



References


1. David M Barrett, Nathan Singh, Xiaojun Liu, Shuguang Jiang, Carl H June, Stephan A Grupp, Yangbing Zhao (2014)Relation of clinical culture method to T-cell memory status and efficacy in xenograft models of adoptive immunotherapy. Cytotherapy. May;16(5):619-30.

2. Barbara Tumaini, Daniel W Lee, Tasha Lin, Luciano Castiello, David F Stroncek, Crystal Mackall, Alan Wayne, Marianna Sabatino. (2013) Simplified process for the production of anti-CD19-CAR-engineered T cells. Cytotherapy 15:1406-1415.


 Trial dosage: A customer can apply for up to five samples a year (the actual trial dosage is determined by telephone or email communication).
Scope of use: Samples are limited to testing and research purposes.
Cost: Free for samples, customer is responsible for shipping and handling charges, reference cost is $50 in the US, €60 in the EU, and $50 in other countries.
How to apply: You can apply by telephone or by email (the email application should specify the sample name, item number, contact person, telephone number, consignee address, etc.).


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